Cardiac Tamponade / Pericardial Effusion – Quick Consult
Last Updated / Reviewed: October 2024

Key History
Key Physical Exam
Risk Factors for Cardiac Tamponade
Differential Diagnosis
Diagnostic Testing
Clinical Risk and Safety Pearls
Treatment

Key History

  • Chest pain, discomfort or fullness
  • Dyspnea on exertion
  • Intolerance to activity
  • Trauma – penetrating cardiac injury
  • History of:
    • MI
    • SLE, RA
    • End stage renal disease
    • Radiation
    • Malignancy
    • Cardiac surgery
    • Pericarditis
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Key Physical Exam

  • Clear lungs
  • Cyanosis
  • Hypotension, distended neck veins, distant heart sounds – Beck’s triad
  • Kussmaul’s sign – rise in jugular venous pressure on inspiration
  • Narrow pulse pressure
  • Precordium with decreased or absent palpable cardiac heave or thrust
  • Pulsus paradoxus
  • RUQ tenderness secondary to hepatic engorgement

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Risk Factors for Cardiac Tamponade

  • Chest trauma
  • HIV
  • Hypothyroidism
  • Iatrogenic – central line placement, pacemaker insertion, cardiac catheterization, pericardiotomy
  • Malignancy – breast, lung, lymphoma, leukemia
  • Post-myocardial infarction – Dressler’s syndrome
  • Rheumatoid arthritis
  • Systemic lupus erythematosus
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Differential Diagnosis

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Diagnostic Testing

Text / literature information and recommendations include:

  • Echocardiography: This is the primary imaging modality for diagnosing cardiac tamponade. It can identify pericardial effusion, right atrial and right ventricular diastolic collapse, and a plethoric inferior vena cava that does not collapse with inspiration. These findings are highly sensitive and specific for tamponade.
  • Hemodynamic Monitoring: Clinical signs such as pulsus paradoxus (an inspiratory decrease in systolic blood pressure greater than 10 mmHg) and elevated jugular venous pressure are important indicators. Hemodynamic monitoring can reveal equalization of diastolic pressures across all cardiac chambers, which is characteristic of tamponade.
  • Electrocardiography (ECG): While not definitive, ECG can show low-voltage QRS complexes and electrical alternans, which are suggestive of large pericardial effusion and tamponade.
  • Computed Tomography (CT): CT can be useful in complex cases to assess the size and location of the effusion, especially when echocardiography is inconclusive. CT findings include a flattened heart, bowing of the interventricular septum, and enlarged superior and inferior vena cava.

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Clinical Risk and Safety Pearls

  • FAST exam at bedside for ED diagnosis of tamponade.
  • Avoid preload reducing medications – nitrates, diuretics.
  • Pericardiocentesis if cardiovascular collapse is imminent.
  • Tamponade is most common in patients with malignant pericarditis.
  • Penetrating cardiac injuries may cause tamponade.
  • Hypovolemic patients with tamponade may not have elevated central venous pressure.
  • Beck’s triad may not be clinically apparent.
  • Large effusions tend to be chronic.
  • Tamponade is more likely with acutely occurring small effusions.

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Treatment

Common text / literature recommendations include:

  • ABCs
  • IV fluids
  • Oxygen
  • Cardiac monitor
  • Vasopressors
  • Pericardiocentesis

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Adler Y, Charron P, Imazio M, et al. 2015 ESC Guidelines for the diagnosis and management of pericardial diseases: The Task Force for the Diagnosis and Management of Pericardial Diseases of the European Society of Cardiology (ESC). Eur Heart J. 2015;36(42):2921-2964.

Alerhand S, Adrian RJ, Long B, Avila J. Pericardial tamponade: A comprehensive emergency medicine and echocardiography review. Am J Emerg Med. 2022 Aug;58:159-174. doi: 10.1016/j.ajem.2022.05.001. Epub 2022 May 6. PMID: 35696801.

Appleton C, Gillam L, Koulogiannis K. Cardiac tamponade. Cardiol Clin.2017;35(4):525-537.

Hoit BD. Pericardial effusion and cardiac tamponade in the new millenium. Curr Cardiol Rep. 2017;19(7):57.

Kearns MJ, Walley KR. Tamponade: Hemodynamic and Echocardiographic Diagnosis. Chest. 2018 May;153(5):1266-1275. doi: 10.1016/j.chest.2017.11.003. Epub 2017 Nov 11. PMID: 29137910.

Klein AL, Abbara S, Agler DA, et al. American Society of Echocardiography clinical recommendations for multimodality cardiovascular imaging of patients with pericardial disease: endorsed by the Society for Cardiovascular Magnetic Resonance and Society of Cardiovascular Computed Tomography. J Am Soc Echocardiogr. 2013; 26:965.

This is intended solely as reference material and is not a recommendation for any specific patient. The practitioner must rely upon his or her own professional judgment and medical decision-making to determine whether it is relevant in a particular case. Materials are derived from medical and nursing texts, medical literature and national guidelines and should not be considered complete or authoritative. Users must rely on specific patient presentation, experience and judgment when utilizing any of the information contained herein relative to an actual patient.

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